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Frequently Asked Questions

Stem Cell / PRP Joint Regeneration

What is Prolotherapy?

Prolotherapy stimulates the body to repair the painful injured area(s) when the body’s natural healing process is not able to do the job on its own. Prolotherapy is an accurate injection of a non-toxic substance into the injured tissue, which causes a temporary and purposeful therapeutic inflammation. The resultant inflammation initiates a beneficial healing cascade causing an increase in blood supply, growth factors, and stem cells. This eventually produces an increase in collagen that essentially grows stronger tissues and cartilage.

What are the Advantages of Stem Cell Prolotherapy?

The advantages of using a solution containing Amniotic Stem Cells, over other traditional therapies, are the astounding physiologic benefits that Stem Cells supplement to the healing cascade. When they are injected into an area that requires wound healing and growth, they are activated to proliferate and differentiate into the needed types of tissue. Stem Cells have the potential to become cartilage, tendon, ligament, bone, and muscle, as well as the ability to promote other healing factors, which are very vital to the repair. These many added benefits make Stem Cells far superior to other elementary solutions, which have traditionally been utilized for Prolotherapy.

What is Platelet Rich Plasma (PRP) Therapy?

The platelets are the specialized blood cells, which are primarily recruited in the blood stream to heal damaged tissues. When an injury occurs, platelets are the true “front-line soldiers” that carry with them many different types of growth factors, proteins, and enzymes, which promote the healing process. They are also the cells that are most responsible for helping to stop the bleeding when tears (sprains) in ligaments and tendons occur. We are able to extract a much higher concentration of these desirable cells from your own blood and when this process is completed, we refer to this rich solution of platelets as “Platelet Rich Plasma”. Then, this “supercharged” solution can be targeted directly into the damaged area. The PRP can be injected alone or in combination with Stem Cells. Ideally, the first Prolotherapy treatment employed for the treatment of a damaged joint would include the combination of Stem Cells with PRP. Subsequent treatments may be necessary, and these follow-up Prolotherapy treatments are usually with PRP alone.

How do we get the PRP from your blood?

A simple blood draw is performed from one of the veins in your arm, similar to what you have done when you have routine labs performed. This blood is then placed in a special centrifuging device that will separate the platelet rich portion of the plasma from the platelet poor portion. This desired PRP portion is then extracted into a syringe and can be mixed with Stem Cells, which have been harvested from the Amniotic Membrane of a live healthy birth.

Where do we get the Stem Cells?

Both Amniotic and Umbilical Cord Stem Cells are supplied by a Bio-engineering company that harvests the cells from the Amniotic Membrane from donor Mothers, who give birth to a live healthy baby. The cells derived from the Amniotic Membrane are composed of many vital growth and healing factors. They have many of the same qualities and potency of Embryonic Stem Cells without any of the ethical dilemmas. they are highly effective, and more potent than your “Adult” cells. They also don’t carry any risks of incompatibility or rejection and undergo the very highest of quality and safety screening.

Our Umbilical Cord Stem Cells are also harvested utilizing advanced tissue collection techniques to create the best minimally manipulated allograft tissue products. Our tissue donor program performs extensive background checks and testing in order to ensure the quality of the donation.

Who can benefit from this therapy?

All patients with various forms of musculoskeletal disorders are prime candidates for these therapies. This includes such conditions as arthritis, tendonitis, ligamentous instability, bursitis, etc. This is a therapy that has been used by elite athletes to return to their sport more quickly and with stronger, healthier tissues. But now it is available for all people with pain and disability in their joints to gain much improved functionality and pain relief.

Who are some of the famous previous recipients of these therapies?

A growing number of elite professional and amateur athletes have been making headlines recently because they have undergone successful treatments with Stem Cell and PRP Prolotherapy. NFL star quaterback Peyton Manning underwent the procedure on his neck in the off-season and had an extremely successful season with his new team, the Denver Broncos, almost winning the NFL MVP award. Star Pittsburgh Steelers wide-receiver, Hines Ward, underwent PRP injections on his knee, which helped him return from an injury and secure the Super Bowl MVP. Tiger Woods had the treatment on his knee and had a successful recovery at the height of his career. Multiple professional baseball pitchers have had these treatments performed on their elbows with excellent results including L.A. Dodger’s pitcher Takashi Saito. The list of well-known sports athletes turning to these cutting edge treatments continues to grow across many different disciplines including such notables as Kobe Bryant, Rafael Nadal, Troy Polamalu, Derrick Rose, Alex Rodriguez, and Cliff Lee. These unsolicited celebrity endorsements have brought to light to the general public the benefits of these procedures, and now more and more people can reap the rewards of having these very same treatments performed on themselves. Utah Stem Cells is finally making these highly coveted and regarded procedures available to everyone, and not just the high profile sports-elite. You don’t have to be a high-level sports professional to enjoy the greater pain relief and functionality that Stem Cell and PRP prolotherapy can provide. In many circumstances less successful and expensive treatments, such as painful surgeries with prolonged recover periods, can be staved off or altogether avoided.

How long does the Stem Cell Prolotherapy procedure take to perform?

The length of time it takes to do one of the Stem Cell Prolotherapy procedures is about an hour. This will include the time it will take to examine and mark the areas to be treated, draw your blood for the PRP, mix it with the Amniotic Stem Cells, and inject your joints and problem areas.

How much pain is involved with the Stem Cell Prolotherapy procedure?

The actual injections are met with minimal discomfort, and local anesthetic is again utilized. This portion of the procedure is typically tolerated well, and you will be able to walk out of the office without any significant pain or difficulties. Nitrous Oxide (“Laughing Gas”) that is commonly used in Dentist’s offices is also available. This can dramatically reduce any pain involved with the actual procedure, as well. After the local anesthetic wears off a few hours later, the discomfort that will develop will be managed with prescribed pain medications. Depending on the area injected, the recovery period in which pain medications may be necessary is usually about two days. The pain will then dramatically subside over the next three to five days and you will return back to your typical baseline pain and function that you were experiencing before the procedure.

How long does it take to appreciate improvements after the Stem Cell Prolotherapy procedure?

Your body will need the next four to six weeks to heal and regenerate the damaged tissue, and you should see significant improvement during this time. It is not unusual for many people to experience much quicker improvement, even within a couple of days, in some joints. However, it is more likely that it will take more time than that and usually will take a couple of weeks to start experiencing significant improvement.

How many treatments are needed?

We will need to re-examine you at the 5–8 week point to see how you are responding to the procedure, and to determine the need for any further treatments. In some cases, additional treatments with PRP alone may be beneficial, but not always required. Once maximal benefit has been achieved, you may continue to enjoy your new pain relief and functionality for several years, many years, or have complete resolution of your symptoms indefinitely. It is different for everyone depending on the degree of the injury that is being treated and individual characteristics.

Why are Human Cell and Tissue Products from Cord Tissue more effective?

Cord tissue mesenchymal stem cells have a faster doubling time than adult mesenchymal stem cells (because they are younger and contain a higher concentration of growth factors).

The fitness of adult mesenchymal stem cells declines with age. Thus Cord tissue mesenchymal stem cells will have greater fitness than adult mesenchymal stem cells (as well as a different profile of growth factors).

stemcellovertime

Are the Stem Cells used in your procedures safe?

263x252
Our Stem Cells are processed in accordance with the standards and regulations set forth by the Food and Drug Administration (FDA) and American Association of Tissue Banks (AATB) for allograft tissue products. Our processes have been developed to preserve the placental tissues’ natural characteristics, including the extracellular matrix, growth factors and inherent cells, and to provide clinically
efficacious products.

Our cells are derived from living, healthy donors that are pre-screened extensively during pregnancy and selected based on our stringent donor suitability criteria. In addition to reviewing pre-natal test results, The Bioengineering company that works with Utah Stem Cells obtains a comprehensive medical
history and behavioral risk assessment from each consenting donor prior to recovery. From aseptic processing to lot
release testing of all of our tissues, we are committed to the safety and quality of our products.

What is an Allograft?

263x252An allograft is tissue from a human donor that is transplanted from one body to another.

Why the Placental Tissues?

263x252Clinicians have used the placental tissues for over a century as a biologic dressing in a broad range of therapeutic applications. It has been generally recognized as a versatile wound covering with published clinical results cited extensively
in the literature. The placental tissues are an abundant source of collagen, as well as the other proteins, growth factors and cells that are essential to support the body’s natural regenerative
healing process. Studies have described the placental tissues as “immuneprivileged”
because they rarely evoke an immune
response in the human body. In addition, studies have shown that the placental tissues may be helpful in treating soft tissue injuries or localized areas of inflammation such as tendiniti

Are There Rists Associated With the Use of BioDRestore?

263x252BioDRestore is an allograft that contains
tissues from a living, healthy donor. As with the implantation of any human tissue, there is always the possibility of an adverse allergic reaction or transmission of
a communicable disease in connection with the use of this product. Over 15,000 allografts distributed by BioD have been
used in dental, ocular, orthopedic and wound care applications.

Is it FDA approved?

CoreCyte™, PolyCyte™, AmnioCyte™ and AmnioCyte Plus™ are processed from donated human tissue from full term deliveries and is regulated as a human cell, tissue, or cellular or tissue-based product (HCT/P) under 21 CFR Part 1271 and Section 361 of the Public Health Service Act.

What are mesenchynal stem cells (MSC)?

Mesenchymal stem cells, or MSCs, are multipotent stromal cells that can differentiate into a variety of cell types, including: osteoblasts (bone cells), chondrocytes (cartilage cells), myocytes (muscle cells) and adipocytes (fat cells).

How do MSC work?

The majority of the effects of MSCs is from trophic effects (exosomes/microvesicles releasing their 3000 growth factors), not from engraftment

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